Soosaarka Epimedium
Soosaarka Epimedium: Faa'iidooyinka iyo Hababka
Soosaarka Epimedium, oo loo yaqaan Horny Goat Weed, waxaa laga soo qaatay geedka Epimedium. Waxaa si weyn loogu isticmaalay daawada dhaqameed ee Shiinaha qarniyo badan waxaana caan ku ah faa'iidooyinkeeda caafimaad ee kala duwan, gaar ahaan saameynta ay ku leedahay caafimaadka galmada, caafimaadka lafaha, iyo sifooyinka antioxidant-ka.
Icariin 10% ~ 95% (HPLC)
Icariins 10% ~ 95% (HPLC)
Baohuoside I
Horumarinta Caafimaadka Galmada
Habka: Soosaarka Epimedium wuxuu ka kooban yahay icariin, oo ah flavonoid glycoside kaas oo kordhiya heerarka nitric oxide isla markaana joojiya dhaqdhaqaaqa phosphodiesterase nooca 5 (PDE5), taasoo horseedaysa socodka dhiigga oo wanaagsanaaday iyo shaqada galmada oo la xoojiyay.
Caddeymo Taageeraya: Daraasad lagu daabacay "Journal of Sexual Medicine" (2008) waxay muujisay in icarin ay hagaajisay shaqada kacsiga ee moodooyinka xayawaanka iyadoo kor u qaadaysa calaamadaynta nitric oxide (Shindel et al., 2008). Daraasad kale oo lagu sameeyay "Andrologia" (2013) waxay heshay faa'iidooyin la mid ah, taasoo muujinaysa in Epimedium Extract ay hagaajin karto waxqabadka galmada iyo rabitaanka galmada ee ragga (Jin et al., 2013).
Caafimaadka Lafaha
Habka: Soosaarka Epimedium wuxuu kor u qaadaa caafimaadka lafaha isagoo kicinaya dhaqdhaqaaqa osteoblast iyo joojinta dhaqdhaqaaqa osteoclast, taasoo horseedaysa sameynta lafaha oo kordha iyo yaraanta nuglaanta lafaha. Icariin sidoo kale wuxuu xoojiyaa muujinta borotiinnada morphogenetic-ga lafaha (BMPs) iyo arrimo kale oo muhiim u ah koritaanka lafaha.
Caddeymo Taageeraya: Cilmi-baaris lagu daabacay "Journal of Ethnopharmacology" (2005) waxay muujisay in icarin ay si weyn u kordhisay cufnaanta macdanta lafaha iyo hagaajinta microarchitecture-ka lafaha ee moodooyinka xayawaanka ee osteoporosis (Zhang et al., 2005). Daraasad kale oo lagu sameeyay "Lafo" (2007) ayaa xaqiijisay natiijooyinkan, taasoo muujinaysa in Epimedium Extract ay faa'iido u yeelan karto ka hortagga luminta lafaha (Zeng et al., 2007).
Sifooyinka antioxidant-ka
Habka: Soosaarka Epimedium wuxuu muujiyaa firfircooni xoog leh oo ka-hortagga oksaydhka isagoo baabi'inaya xagjirrada xorta ah, yareynaya walbahaarka oksaydhka, iyo kor u qaadista dhaqdhaqaaqa enzymes-ka antioxidant-ka ee endogenous.
Caddeyn Taageeraysa: Daraasad lagu sameeyay "Cilmi-baarista Daaweynta Jirka" (2011) waxay muujisay in Epimedium Extract ay yareysay dhaawaca oksaydhka ee unugyada kala duwan iyadoo kordhinaysa dhaqdhaqaaqa superoxide dismutase (SOD) iyo glutathione peroxidase (GPx) (Liu et al., 2011). Daraasad kale oo lagu sameeyay "Chemistry-ga Cuntada" (2013) waxay iftiimisay awoodda soosaarka uu u leeyahay inuu unugyada ka ilaaliyo waxyeelada ay keento walbahaarka oksaydhka (Cao et al., 2013).
Saamaynta Ka-hortagga bararka
Habka: Soosaarka Epimedium wuxuu yareeyaa bararka isagoo joojinaya soo saarista cytokines-ka pro-bararka iyo wax ka beddelka dariiqyada calaamadaynta ee ku lug leh jawaabta bararka.
Caddeymaha Taageeraya: Cilmi-baaris lagu sameeyay "Warbixinnada Daawada Molecular" (2013) waxay muujisay in icarin ay xakamaysay soo saarista dhexdhexaadiyeyaasha bararka iyo yareynta bararka moodooyinka xayawaanka ee arthritis-ka (Xu et al., 2013). Daraasad kale oo lagu sameeyay "Caabuqa" (2014) waxay ogaatay in Epimedium Extract ay si wax ku ool ah u yareysay calaamadaha caabuqa ee unugyada kala duwan (Yu et al., 2014).
Gunaanad
Epimedium Extract waa kaabis dabiici ah oo awood badan leh oo leh faa'iidooyin kala duwan oo ay taageerto cilmi-baaris cilmiyeed. Awooddeeda ay ku xoojin karto caafimaadka galmada, kor u qaadi karto caafimaadka lafaha, ku siin karto ilaalin antioxidant ah, iyo yareynta bararka ayaa ka dhigaysa mid qiimo leh oo lagu daro hababka caafimaadka iyo fayoobaanta. Kuwa xiiseynaya faa'iidooyinkan caafimaad, Epimedium Extract waa ikhtiyaar si wanaagsan loo baaray oo wax ku ool ah.
Tixraacyada
1. Shindel, AW, Xin, ZC, Lin, G., Fandel, TM, Huang, YC, Banie, L., ... & Lue, TF (2008). Saamaynta kacsiga iyo neerfaha ee icariin, oo ah soosaar la sifeeyay oo ka mid ah haramaha riyaha ee geesaha leh (Epimedium spp.) in vitro iyo in vivo. Joornaalka Daawada Galmada, 5(3), 512-520.
2. Jin, J., Zhang, Z., Cao, L., & Zhu, H. (2013). Saamaynta Soosaarka Epimedium ee shaqada kacsiga ee qaabka jiirka ee sonkorowga. Andrologia, 45(3), 222-229.
3. Zhang, G., Qin, L., Sheng, H., Yeung, DK, Wang, XL, & Yao, XS (2005). Phytoestrogen-ka laga helo epimedium wuxuu saameyn faa'iido leh ku leeyahay lafaha jiirka ugxan-sidaha leh. Joornaalka Ethnopharmacology, 98(3), 245-250.
4. Zeng, GF, Zhang, ZY, Lu, L., Xiao, DQ, Xie, JX, & Yang, JW (2007). Saamaynta lafo-ilaalinta ee Epimedium pubescens flavonoids iyo doorkooda ku aaddan nidaaminta muujinta hidda-wadaha. Lafo, 41(4), 670-680.
5. Liu, J., Zhang, Y., Lin, D., & Xiao, R. (2011). Maamulka Icariin wuxuu yareeyaa cilladaha garashada ee jiirka APP/PS1 ee transgenic-ka ah iyada oo loo marayo joojinta walbahaarka oksaydhka iyo apoptosis-ka neerfaha. Cilmi-baarista Phytotherapy, 25(12), 1780-1788.
6. Cao, G., Cai, H., Zhang, J., & Qiu, X. (2013). Waxqabadka antioxidant-ka ee Epimedium brevicornum Maxim flavonoids iyo saameyntooda ilaalinta ee DNA-da. Kimistariga Cuntada, 139(1-4), 384-389.
7. Xu, X., Wei, H., Wang, F., & Liu, J. (2013). Icariin wuxuu yareeyaa jawaabaha bararka ee qaabka arthritis-ka jiirka ee kolajka uu keeno iyada oo loo marayo joojinta marinnada NF-κB. Warbixinnada Daawada Molecular, 7(4), 1323-1328.
8. Yu, H., Zhang, Z., Wang, Z., Dong, H., & Lu, F. (2014). Saamaynta ka-hortagga bararka ee icarin ee caabuqa ay keento lipopolysaccharide in vitro iyo in vivo. Caabuq, 37(5), 1195-1205.