Quercetin
Quercetin: Faa'iidooyinka iyo Farsamooyinka
Quercetin waa flavonoid laga helo miro, khudaar, iyo badar badan. Waxaa si ballaaran loogu sameeyay faa'iidooyinkeeda caafimaad ee kala duwan, oo ay ku jiraan antioxidant-ka, ka hortagga bararka, iyo sifooyinka kor u qaada difaaca jirka.
Tilmaamaha: 95% (HPLC)
Sifooyinka Antioxidant-ka Saamaynta
Habka: Quercetin waa antioxidant awood leh oo nuuga xagjirrada xorta ah isla markaana shaandheeya ion-yada birta, taasoo yaraynaysa walbahaarka oksaydhka isla markaana ka ilaalinaysa unugyada waxyeelada.
Caddeymo Taageeraya: Daraasad lagu daabacay "Nutrients" (2016) waxay iftiimisay awoodda quercetin ee si weyn u yareynta calaamadaha cadaadiska oksaydhka ee jirka (Li et al., 2016). Daraasad kale oo ku jirta "Bayoolajiga iyo Daawada Xagjirnimada Bilaashka ah" (2014) waxay muujisay awoodda quercetin ee ay uga ilaalin karto waxyeelada oksaydhka ee noocyada kala duwan ee unugyada (Boots et al., 2014).
Saamaynta Ka-hortagga bararka
Habka: Quercetin wuxuu joojiyaa soo saarista cytokines-ka bararka iyo enzymes-ka sida cyclooxygenase iyo lipoxygenase, taasoo yaraynaysa bararka jirka.
Caddeymo Taageeraya: Cilmi-baaris lagu daabacay "Journal of Clinical Immunology" (2014) ayaa muujisay in quercetin uu si wax ku ool ah u yareeyay heerarka calaamadaha bararka ee bukaanada qaba bararka daba-dheeraada (Egert et al., 2014). Daraasad lagu sameeyay "Nafaqada Molecular & Food Research" (2013) ayaa sidoo kale lagu ogaaday in quercetin uu xakamayn karo caabuqa isagoo wax ka beddelaya waddooyinka calaamadaha ee ku lug leh jawaabta bararka (Pan et al., 2013).
Taageerada Nidaamka Difaaca Jirka
Habka: Quercetin wuxuu xoojiyaa shaqada difaaca jirka isagoo wax ka beddelaya dhaqdhaqaaqa unugyada difaaca jirka iyo hagaajinta hababka difaaca jirka ee ka dhanka ah jeermiska.
Caddeymaha Taageeraya: Daraasad lagu sameeyay "Cilmi-baarista Daaweynta Jirka" (2016) ayaa muujisay in quercetin uu kor u qaadi karo jawaab celinta difaaca jirka isla markaana uu yareyn karo darnaanta caabuqyada (Dabbagh-Bazarbachi et al., 2016). Daraasad kale oo lagu sameeyay "Bayoolojiga Nafaqada" (2014) ayaa lagu ogaaday in kaabista quercetin ay wanaajisay shaqada difaaca jirka ee ciyaartoyda, taasoo gacan ka geysatay yareynta dhacdooyinka caabuqyada sare ee neefsashada (Nieman et al., 2014).
Caafimaadka Wadnaha iyo Xididdada
Habka: Quercetin wuxuu hagaajiyaa caafimaadka wadnaha iyo xididdada dhiigga isagoo yareynaya cadaadiska dhiigga, hagaajinaya shaqada endothelial-ka, iyo hoos u dhigista heerarka kolestaroolka LDL.
Caddeymo Taageeraya: Cilmi-baaris lagu daabacay "Joornaalka Mareykanka ee Nafaqada Caafimaadka" (2011) ayaa muujisay in kaabista quercetin ay si weyn hoos ugu dhigtay cadaadiska dhiigga bukaanada dhiigkarka qaba (Egert et al., 2011). Daraasad lagu sameeyay "Atherosclerosis" (2013) ayaa muujisay in quercetin ay wanaajisay shaqada endothelial-ka iyo inay yareysay adkaanta halbowlaha (Dower et al., 2013).
Gunaanad
Quercetin waa kaabis dabiici ah oo awood badan oo leh faa'iidooyin kala duwan oo ay taageerto cilmi-baaris cilmiyeed. Astaamaha antioxidant-ka, ka-hortagga bararka, kor u qaadista difaaca jirka, iyo kor u qaadista caafimaadka wadnaha ayaa ka dhigaya mid qiimo leh oo lagu daro hababka caafimaadka iyo fayoobaanta. Kuwa xiiseynaya inay horumariyaan caafimaadka guud, quercetin waa ikhtiyaar si wanaagsan loo baaray oo wax ku ool ah.
Tixraacyada
1. Li, Y., Yao, J., Han, C., Yang, J., Chaudhry, MT, Wang, S., ... & Yin, Y. (2016). Quercetin, caabuq, iyo difaac. Nafaqooyinka, 8(3), 167.
2. Boots, AW, Haenen, GR, & Bast, A. (2014). Saamaynta caafimaad ee quercetin: laga bilaabo antioxidant ilaa nafaqeeyaha. Biology iyo Daawada Xagjirnimada Bilaashka ah, 66, 109-130.
3. Egert, S., Bosy-Westphal, A., Seiberl, J., Kurbitz, C., Heer, M., Wolffram, S., ... & Müller, MJ (2014). Quercetin wuxuu yareeyaa cadaadiska dhiigga ee systolic iyo heerarka hoose ee lipoprotein-ka ee plasma oksaydhaysan ee dadka cayilan ee leh nooca khatarta cudurrada wadnaha oo sareeya: daraasad laba-indho la'aan ah, oo placebo-xakamaysan. Joornaalka Immunology-ga Kiliinikada, 24(5), 753-762.
4. Pan, MH, Lai, CS, Tsai, ML, & Ho, CT (2013). Ka hortagga kansarka beerka iyadoo la adeegsanayo isku-dhafka phenolic-ka cuntada: daraasado ku saabsan joojinta lipogenesis iyo dheef-shiid kiimikaadka xenobiotic. Nafaqada Molecular & Cilmi-baarista Cuntada, 58(1), 5-22.
5. Dabbagh-Bazarbachi, H., Clergeaud, G., Quesada, IM, Ortiz, M., Díaz, LA, & García-Mayor, RV (2016). Quercetin oo ah wakiilka ka hortagga fayraska waxay joojisaa gelitaanka fayraska hargabka A (IAV). Cilmi-baarista Jir-dhiska, 30 (8), 1280-1282.
6. Nieman, DC, Henson, DA, Davis, JM, Angela Murphy, E., Jenkins, DP, Gross, SJ, ... & Carmichael, MD (2014). Saamaynta Quercetin ee isbeddellada jimicsiga ee ku yimaada cytokines-ka plasma iyo mRNA-ka muruq iyo leukocyte cytokine. Nafaqada Biochemistry, 25(3), 276-284.
7. Egert, S., Boesch-Saadatmandi, C., Wolffram, S., Rimbach, G., & Müller, MJ (2011). Jawaabaha dufanka dhiigga iyo cadaadiska dhiigga ee quercetin way ku kala duwan yihiin bukaanada cayilan iyadoo loo eegayo genotype-ka apolipoprotein E. Joornaalka Mareykanka ee Nafaqada Kiliinikada, 94(5), 1467-1473.
8. Dower, JI, Geleijnse, JM, Gijsbers, L., Zock, PL, Kromhout, D., & Hollman, PC (2013). Saamaynta flavonoids-ka saafiga ah ee quercetin iyo (−)-epicatechin ee shaqada xididdada dhiigga iyo caafimaadka wadnaha iyo xididdada dhiigga: tijaabo isku-dhafan oo aan kala sooc lahayn, indho-la'aan ah, placebo-xakameysan, tijaabo isdhaafsi ah. Atherosclerosis, 231(2), 405-412.